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SCIENCE, STANDARDS & RAPID RESPONSE

VITAMIN & MINERAL SAFETY BOOK: GLOBAL BENCHMARK FOR SCIENCE-BASED LEVEL-SETTING

CRN released updated chapters in its Vitamin and Mineral Safety handbook for folic acid (+methylfolate), iron, magnesium, potassium, selenium, vitamin A, B3, B6, E, and zinc, along with a revised methodology chapter to reflect the latest scientific standards. First-time evaluations for choline (including citicoline) and lutein/zeaxanthin/meso-zeaxanthin were also published, alongside a new section on methylfolate and confirmation of vitamin K2’s established safety record.

These new and updated evaluations help ensure that stakeholders have access to current and credible scientific information on the safety of these nutrients.

NEW TASK FORCES FOR TURMERIC AND GRAS + REGULATORY ENGAGEMENT

CRN convened a Turmeric Task Force to consider development of a voluntary program, around formulation and labeling.

CRN launched a GRAS Task Force and met with FDA Deputy Commissioner Kyle Diamantas early in the year, then hosted Diamantas for a board meeting fireside chat in Q4 on GRAS rulemaking, drug preclusion, and MAHA influence, in addition to participating in several key meetings with regulatory officials.

 

DEFENDING SCIENCE IN THE SPOTLIGHT—CRN’s RAPID RESPONSE TO INACCURACIES

CRN countered flawed research methodologies and alarmist media narratives with evidence-based responses. For example, the science team challenged Clean Label Project’s Protein Study 2.0 for lacking transparency and context and corrected PLOS Mental Health’s misrepresentation of muscle-building supplements and adolescent mental health. CRN also clarified that vitamin A doesn’t prevent measles following reports of some parents administering high doses to their children. This proactive approach—resulting in citations across major outlets—demonstrated industry commitment to scientific integrity while protecting consumers from fear-based narratives that discourage beneficial supplement use.

 


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