Vitamin K2 Users Get Good News: CRN’s New Analysis Confirms Strong Safety Record for MK-7 Supplements
November 20, 2025 - The CRN Foundation today announced the release of CRN’s updated Vitamin K2 (menaquinone-7, MK-7) chapter as part of the Vitamin & Mineral Safety, 4th Edition (VMS4). For the first time, CRN’s rigorous safety evaluation establishes a supplemental Highest Observed Intake (HOI) level of 375 µg/day for adults, offering essential new guidance for manufacturers, regulators, and health practitioners seeking evidence-based recommendations for this increasingly used nutrient.
