Free for CRN members / $299 for non-members
Discover how non-animal methods and emerging NAMs are transforming ingredient safety assessment in this two-part CRN webinar series.
Animal testing has long been the foundation of safety assessments, but its limitations—and growing consumer scrutiny—are driving change. At the same time, scientific advances are transforming how toxicologists evaluate dietary supplement ingredient safety without relying on animal data.
This two-part CRN webinar series will equip attendees with the knowledge needed to navigate this shift. Experts will explain how established non-animal methods, such as threshold of toxicological concern (TTC) and read-across, have supported safety decisions and where their limitations remain. The program will then explore emerging non-animal methods (NAMs), including Omics technologies, in silico models, and AI-enabled tools that are reshaping modern toxicology.
With:
Seneca Fitch, Director, Health Sciences, Managing Scientist, ToxStrategies
Seneca Fitch is a Managing Scientist and Director of ToxStrategies’ Health Sciences Practice, specializing in systematic evaluations of substances linked to consumer products, food additives, pharmaceuticals, and industrial chemicals. As an expert information specialist and evidence analyst, she supports the entire systematic review process, from problem formulation and protocol development to data extraction, critical appraisal, and evidence synthesis. Her current research focuses on automating systematic reviews in environmental and health-related risk assessments, integrating artificial intelligence and machine learning to optimize literature prioritization, evidence mapping, and systematic reviews. As a practitioner, Ms. Fitch has extensive hands-on experience with leveraging informatics platforms and custom AI-facilitated approaches to answer specific research questions. She is an active participant in the Evidence-Based Toxicology Collaboration, serving on its scientific advisory council and as Chair of the Research Methods Working Group. Ms. Fitch has co-authored 20 peer-reviewed publications and 2 book chapters, contributing to advancements in evidence-based toxicology and modern approaches to evidence synthesis.
Fred Lozy, Ph.D., Scientific Consultant II, Safety and Regulatory Affairs, Intertek Assuris
Dr. Fred Lozy is a scientific, safety, and regulatory consultant providing support to clients with extensive experience in a variety of categories including HMOs, pre- and probiotics, cell-cultured ingredients, and supplements in the United States, Canada, European Union, Asia, and other countries. Dr. Lozy ensures the safety of food, supplement, and nutrition ingredients by reviewing available data confirming quality and compliance with the appropriate regulatory regulations, including expertise in food and dietary supplement labeling compliance. In order to help our clients successfully obtain regulatory access to markets around the world, Dr. Lozy compiles regulatory documents such as Generally Recognized as Safe dossiers (GRAS), New Dietary Ingredient Notifications (NDIN), Novel Food submissions, feasibility, and risk assessments for submission to regulatory agencies.
Connie Mitchell, MS, Senior Scientific Program Manager, HESI Global
Connie A. Mitchell is a Senior Scientific Program Manager at HESI Global. Prior to joining HESI in early 2020, she was an ORISE Fellow at the US Environmental Protection Agency working on chemical prioritization under the Toxic Substances Control Act. She completed her graduate studies in Environmental Toxicology at the University of California Riverside. As a Senior Scientific Program Manager, she provides scientific, strategic, and management support to collaborative scientific committees involving academic, government, nonprofit, and private sector scientists. She manages the Botanical Safety Consortium (BSC).
Grace Patlewicz, Ph.D., Senior Science Advisor, ToxStrategies
Grace Patlewicz is a computational toxicologist and chemist by training specialising in mammalian toxicity. Dr. Patlewicz’s research interests have focused on developing and applying (Q)SARs and read-across for regulatory purposes. She has chaired various industry, ICCVAM workgroups and has significantly contributed to technical guidance for (Q)SARs, chemical categories, and Adverse Outcome Pathways (AOPs) under various Organisation for Economic Co-operation and Development (OECD) work programmes. Before joining ToxStrategies, Dr. Patlewicz started her toxicology career at Unilever United Kingdom before moving to the European Commission Joint Research Centre in Italy and then to DuPont and the Environmental Protection Agency (EPA) in the United States. She is an Adjunct Professor in the Department of Environmental Sciences and Engineering (ESE) at the University of North Carolina (UNC), Chapel Hill, US. She has published extensively in the peer reviewed literature (~185 journal publications and book chapters) and has presented nationally and internationally at scientific conferences and meetings.
Adam Wood, Scientist - Human Safety, Unilever
Adam Wood is a safety scientist/toxicologist who has been working in Unilever's Safety, environment and regulatory sciences (SERS) team in the UK for over 5 years and prior to this worked as a toxicologist for Boots for around 2 years following the completion of his undergraduate and masters in Pharmacology from the University of Liverpool in the UK. At Unilever, Adam has experience in the safety assessment of many different product types across Unilever's portfolio, such as foods (including food supplements), cosmetics and cleaning products. He also works in the development and application of new approach methods (NAMs) as part of Unilever's ongoing efforts relating to next generation risk assessment (NGRA) particularly in the areas of food safety and occupational safety. Through the former, Adam recently led a FoodDrinkEurope task force on NAMs, which reviewed NAMs applicable to food safety and made suggestions to enhance their use in the EU food safety environment to contribute to the EU roadmap to phase out animal testing.
Free for CRN members / $299 for non-members
View the CRN webpage for part two.
